Lumpp

Tatjana Lumpp

Research focus

Epigenetic influence of carcinogenic metal compounds on DNA repair genes considering post-translational histone modifications

  • Investigation of metal-induced chromatin changes with regard to chromatin accesibillity as well as global and gene-specific histone modification patterns

  • Gene expression analysis

  • Cytotoxicity studies
 
 

Methods

  • Gene-specific analysis of histone modifications by ChIP-qPCR

  • Gene expression profiling using high-throughput RT-qPCR

  • Cytotoxicity assays

  • Quantification of metals using AAS

  • Protein analysis via immunoblot

  • Immunofluorescence experiments

Teaching

  • Supervision of master thesis, term papers and bachelor thesis

  • Supervision of teaching lab "Toxikologisches Praktikum" (AAS & Electrophoresis)