Tatjana Lumpp
- Group: Epigenetics
- Room: 123
- Phone: +49 721 608-42942
- tatjana lumpp ∂does-not-exist.kit edu
Research focus
Epigenetic influence of carcinogenic metal compounds on DNA repair genes considering post-translational histone modifications
-
Investigation of metal-induced chromatin changes with regard to chromatin accesibillity as well as global and gene-specific histone modification patterns
-
Gene expression analysis
-
Cytotoxicity studies
Methods
-
Gene-specific analysis of histone modifications by ChIP-qPCR
-
Gene expression profiling using high-throughput RT-qPCR
-
Cytotoxicity assays
-
Quantification of metals using AAS
-
Protein analysis via immunoblot
-
Immunofluorescence experiments
Teaching
-
Supervision of master thesis, term papers and bachelor thesis
-
Supervision of teaching lab "Toxikologisches Praktikum" (AAS & Electrophoresis)
Publications
Lumpp, T.; Stösser, S.; Fischer, F.; Hartwig, A.; Koberle, B. Role of Epigenetics for the Efficacy of Cisplatin. International Journal of Molecular Sciences 2024
Stösser, S.; Lumpp, T.; Fischer, F.; Gunesch, S.; Schumacher, P.; Hartwig, A. Effect of Long-Term Low-Dose Arsenic Exposure on DNA Methylation and Gene Expression in Human Liver Cells. International Journal of Molecular Sciences 2023