Tatjana Lumpp

Research focus

Epigenetic influence of carcinogenic metal compounds on DNA repair genes considering post-translational histone modifications

  • Investigation of metal-induced chromatin changes with regard to chromatin accesibillity as well as global and gene-specific histone modification patterns

  • Gene expression analysis

  • Cytotoxicity studies


  • Gene-specific analysis of histone modifications by ChIP-qPCR

  • Gene expression profiling using high-throughput RT-qPCR

  • Cytotoxicity assays

  • Quantification of metals using AAS

  • Protein analysis via immunoblot

  • Immunofluorescence experiments


  • Supervision of master thesis, term papers and bachelor thesis

  • Supervision of teaching lab "Toxikologisches Praktikum" (AAS & Electrophoresis)



Lumpp, T.; Stösser, S.; Fischer, F.; Hartwig, A.; Koberle, B. Role of Epigenetics for the Efficacy of Cisplatin. International Journal of Molecular Sciences 2024

Stösser, S.; Lumpp, T.; Fischer, F.; Gunesch, S.; Schumacher, P.; Hartwig, A. Effect of Long-Term Low-Dose Arsenic Exposure on DNA Methylation and Gene Expression in Human Liver Cells. International Journal of Molecular Sciences 2023