Research Focus

  • Impact of toxic metal compounds to cellular proteins
  • Identification and quantification of redox sensitive protein structures
  • Correlation of protein modifications and gene expression
  • Cytotoxicity studies
  • Analyse posttranslational protein modifications using LC-MS/MS
  • Gene expression profiling using high-throughtput RT-qPCR
  • Cytotoxicity assays


  • Supervision of Master ans Bachelor thesis
  • Supervision of teaching tab "Biochemistry (PCR)"


Wall J., Ag Seleci D., Schworm F., Neuberger R., Link M., Hufnagel M., Schumacher P., Schulz F., Heinrich U., Wohlleben W., Hartwig A.
Comparison of Metal-Based Nanoparticles and Nanowires: Solubility, Reactivity, Bioavailability and Cellular Toxicity 
Nanomaterials  (2021)

Hufnagel M., Neuberger R., Wall J., Link M., Friesen A., Hartwig A.
Impact of Differentiated Macrophage-Like Cells on the Transcriptional Toxicity Profile of CuO Nanoparticles in Co-Cultured Lung Epithelial Cells
International Journal of Molecular Sciences (2021)