Research Focus
- Impact of toxic metal compounds to cellular proteins
- Identification and quantification of redox sensitive protein structures
- Correlation of protein modifications and gene expression
- Cytotoxicity studies
Methods
- Analyse posttranslational protein modifications using LC-MS/MS
- Gene expression profiling using high-throughtput RT-qPCR
- Cytotoxicity assays
Publications
Wall J., Ag Seleci D., Schworm F., Neuberger R., Link M., Hufnagel M., Schumacher P., Schulz F., Heinrich U., Wohlleben W., Hartwig A.
Comparison of Metal-Based Nanoparticles and Nanowires: Solubility, Reactivity, Bioavailability and Cellular Toxicity
Nanomaterials (2021)
Hufnagel M., Neuberger R., Wall J., Link M., Friesen A., Hartwig A.
Impact of Differentiated Macrophage-Like Cells on the Transcriptional Toxicity Profile of CuO Nanoparticles in Co-Cultured Lung Epithelial Cells
International Journal of Molecular Sciences (2021)