Research Focus
Proteomics
- Study compounds: anorganic and organic selenium compounds as well as silver nanoparticles in comparison to watersoluble silver
- Impact of selenium and silver compounds on the proteome of human liver cells
- Influence of various selenium compounds including organic and anorganic compounds
- Distinction between potential protective and toxic effects of selenium compounds (concentration-dependently)
- Identification of redox-sensitive proteins
Methods
- Cell Culture
- Cytotoxicity Assays
- LC-MS/MS
- High-throughput RT-qPCR
- Western Blot
Teaching
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Supervision of master and bachelor thesis as well as seminar papers
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Supervision of the biochemical internship (Master Food Chemistry, "Elektrophorese")
Publications
Fischer, F.; Stößer, S.; Wegmann, L.; Veh, E.; Lumpp, T.; Parsdorfer, M.; Schumacher, P.; Hartwig, A Chromate Affects Gene Expression and DNA Methylation in Long-Term In Vitro Experiments in A549 Cells. https://doi.org/10.3390/ijms251810129 (2024)