Sandra Stößer
- Group: Epigenetics
- Room: 123
- Phone: +49 721 608-42942
- sandra stoesser ∂does-not-exist.kit edu
Research focus
Investigations of epigenotoxic effects of metal compounds on genes of DNA repair considering differential methylation patterns
- Investigation of metal-induced changes in gene-specific and global DNA methylation patterns
- Gene expression analysis
- Cytotoxicity studies
Methods
- Methylation Specific PCR (MSP)
- Methylation-Sensitive High Resolution Melting (MS-HRM)
- Gene expression profiling using high-throughput RT-qPCR
- Cytotoxicity assays
- Quantification by HPLC (nucleosides)
Teaching
- Supervision of master thesis, term papers and bachelor thesis
- Supervision of "Lebensmittelchemisches Praktikum II"
Publications
Fischer, F.; Stößer, S.; Wegmann, L.; Veh, E.; Lumpp, T.; Parsdorfer, M.; Schumacher, P.; Hartwig, A. Chromate Affects Gene Expression and DNA Methylation in Long-Term In Vitro Experiments in A549 Cells. https://doi.org/10.3390/ijms251810129 (2024)
Lumpp T., Stösser S., Fischer F., Hartwig A., Köberle B.
Role of Epigenetics for the Efficacy of Cisplatin
International Journal of Molecular Sciences 2024
Stösser S., Lumpp T., Fischer F., Gunesch S., Schumacher P., Hartwig A.
Effect of Long-Term Low-Dose Arsenic Exposure on DNA Methylation and Gene Expression in Human Liver Cells
International Journal of Molecular Sciences 2023
Matthäus T., Stösser S., Seren H. Y., Haberland V. M. M., Hartwig A.
Arsenite Impairs BRCA1-Dependent DNA Double-Strand Break Repair, a Mechanism Potentially Contributing to Genomic Instability
International Journal of Molecular Sciences 2023