Abteilung für Lebensmittelchemie und Toxikologie

Publikationen

Schoch, S., Seb V., Gajewski S., Golubev V., Strauch B., Hartwig A., Köberle B.

Acitivity profile of the cisplatin analogue PN149 in different tumor cell

Biochemical Pharmacology (2018)

 

Cetraz M., Sen V., Schoch S., Streule, K., Golubev V., Hartwig A., Köberle B.

Platinum(IV)-nitroxyl complexes as possible candidates to circumvent cisplatin resistance in RT112 bladder cancer cells

Archives of Toxicology (2016) (Epub ahead of print)

 

Usanova S., Piee-Staffa A., Sied U., Thomale J., Schreiber A., Kaina B., Köberle B.

Cisplatin sensitivity of testis tumor cells is due to dericiency in interstrand-crosslink repair and low ERCC1-XPF expression.

Mol Cancer 9, 248 (2010)

 

Köberle B., Ditz C., Kausch I., Wollenberg B., Ferris R.L., Albers A.

Metastases of squamous cell carcinoma of the head and neck show increased levels of nucleotide excision repair protein XPF in vivo that correlate with increased chemoresistance ex vivo.

Int J Oncology 36, 1277-1284 (2010)

 

Köberle B., Roginskaya V., Zima K.S., Masters J.R., Wood R.D.

 

Elevation of XPA protein level in testis tumor cells without increasing resistance to cisplatin or UV irradiation.

Mol Carcinogenesis 47, 580-586 (2008)

 

Köberle B., Roginskaya V., Wood R.D.

XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells.

DNA Repair 5, 641-648 (2006)

 

Welsh C., Day R., McGurk C., Masters J.R.W., Wood R.D., Köberle B.

Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines.

Int J Cancer 110, 352-361 (2004)

 

Köberle B., Masters J.R.W., Hartley J.A., Wood R.D.

Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumors.

Current Biol 9, 273-276 (1999)

 

Köberle B., Grimaldi K.A., Sunters A., Hartley J.A., Kelland L.R., Masters J.R.W.

DNA repair capacity and cisplatin-sensitivity of human testis tumor cells.

Int J Cancer 70, 551-555 (1997)

 

Köberle B., Payne J., Grimaldi K.A., Hartley J.A., Kelland L.R., Masters J.R.W.

DNA repair in cisplatin-sensitive and resistant human cell lines measured in specific genes by quantitative polymerase chain reaction.

Biochem Pharmacol 52, 1729-1734 (1996)

 

Köberle B., Haupter S., Just W. Speit G.

Mutation screening of bleomycin-induced V79 Chinese hamster mutants using multiplex polymerase chain reaction (PCR).

Mutagenesis 6, 527-531 (1991)

 

Köberle B., Speit G.

The effect of glutathione depletion on sister-chromatid exchange induction by cytostatic drugs.

Mutat Res. 243, 225-231 (1990)

 

 

Reviews

 

Köberle B., Koch B., Fischer B.M., Hartwig A.

Single nucleotide polymorphisms in DNA repair genes and putative cancer risk.

Arch Toxicol 90, 2369-2388 (2016) DOI:10.1007/s00204-016-1771-2.

 

Albers A.E., Chen C., Köberle B., Qian X., Klussmann J.P., Wollenberg B., Kaufmann A.M.

Stem cells in squamous head and neck cancer.

Critical Reviews in Oncology/Hematology 81, 224-240 (2012)

 

Köberle B., Tomicic M., Usanova S., Kaina B.

Cisplatin: Preclinical findings and clinical implications.

BBA Reviews on Cancer 1806, 172-182 (2010)

 

Masters J.R.W., Köberle B.

Curing metastatic cancer: lessons from testicular germ-cell tumours.

Nature Review Cancer 3, 517-525 (2003)

 

Wood R.D., Araújo S.J., Batty D.P., Biggerstaff M., Evans E., Gaillard P.-H., Gunz D., Köberle B., Kuraoka I., Moggs J.G., Sandall J.K., Shivji M.K.K.

DNA damage recognition and nucleotide excision repair in mammalian cells.

Cold Spring Harbor Sym. Quant. Biol. 65, 173-182 (2000)

 

 

Books

 

Hartwig A., Köberle B., Michalke B.

Nutzen-Risiko-Bewertung von Mineralstoffen und Spurenelementen: Biochemische, physiologische und toxikologische Aspekte.

KIT-Verlag, Karlsruhe (2014)

 

 

 

Book chapters

 

Köberle B., Piee-Staffa A.

The molecular basis of cisplatin resistance in bladder cancer cells.

Chapter in "Bladder Cancer – From basic science to robotic surgery" InTech Open access Publisher (2011)

 

Köberle B., Wittschieben J.P., Wood R.D.

DNA repair and cancer.

Chapter 4 in "Cellular and Molecular Biology of Cancer" 4th Edition, Oxford University Press (2005)