Abteilung für Lebensmittelchemie und Toxikologie

2016-2020

Witkiewicz-Kucharczyk A., Goch W., Oledzki J., Hartwig A., Bal W.

The reaction of H2O2 and GSNO with the zinc finger motif of XPA. Not a regulatory mechanism, but no synergy with cydmium toxicity

Molecules (2020)
 

Schoch S., Gajewski S., Rothfuß J., Hartwig A., Köberle B.

Comparative study of the mode of action of clinically approved platinum-based chemotherapeutics

 

Aberle L., Krüger A., Reber J., Lippmann M., Hufnagel M., Schmalz M., Trussina I., Schlesiger S., Zubel T., Schütz K., Marx A., Hartwig A., Ferrando-May E., Bürkle A., Mangerich A.

PARP1 catalytic variants reveal beanching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response

 

Gajewski S., Hartwig A.

PARP1 is required for ATM-mediated p53 acivation and p53-mediated gene expression after ionizing radiation

Chemical Research in Toxicology (2020)

 

Hartwig A., Arand M., Epe B., Guth S., Jahnke G., Lampen A., Martus H.-J., Monien B., Rietjens I. M. C. M., Schmitz-Spanke S., Schriever-Schwemmer G., Steinberg P., Eisenbrand G.

Mode of action-based risk assessment of genotoxic carcinogens

Archives of Toxicology (2020)

 

Hufnagel M., Schoch S., Wall J., Strauch B.M., Hartwig A.

Toxicity and Gene Expression Profiling of Copper- and Titanium-Based Nanoparticles Using Air-Liquid-Interface Exposure

Chemical Research in Toxicology (2020)

 

Strauch B.M., Hubele W., Hartwig A.

Impact of Endocytosis and Lysosomal Acidification on the Toxicity of Copper Oxide Nano- and Microsized Particles: Uptake and Gene Expression Related to Oxidative Stress and the DNA Damage Response

Nanomaterials (2020)

 

Hufnagel M., Niemand R.K., Strauch B.M., Hartwig A.

Essentielle Spurenelemente und toxische Metallverbindungen

Chemie in unserer Zeit (2019)

 

Laube B., Michaelsen S., Meischner V., Hartwig A., Epe B., Schwarz M.

Classification or non-classification of substances with positive tumor findings in animal studies: Guidance by the German MAK commission

Regulatory Toxicology and Pharmacology (2019)

 

Ott D.B., Hartwig A., Stilman M.J.

Competition between Al3+ und Fe3+ binding to human transferin and toxicological implications: Structural investigations using ultra-high resolution ESI MS and CD spectroscopy

Metallomics (2019)

 

Weber S., Schmidt T., Schumacher P., Kuballa T., Mildau G., Walch S. G., Hartwig A. Lachenmeier D. W.

Quantification of Mineral Oil Aromatic Hydrocarbons (MOAH) in Anhydrous Cosmetics Using 1H NMR

Journal Of Chemistry (2019)

Schoch S., Seb V., Gajewski S., Golubev V., Strauch B., Hartwig A., Köberle B.

Acitivity profile of the cisplatin analogue PN149 in different tumor cell

Biochemical Pharmacology (2018)

 

Fischbach A., Kruger A., Hampp S., Assmann G., Rank L., Hufnagel M., Stockl M. T. , Fischer J. M. F. , Veith S., Rossatti P., Ganz M., Ferrando-May E., Hartwig A., Hauser K., Wiesmuller L., Burkle A., Mangerich A.

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1

Nucleic Acids Research (2018)

Hartwig A., Drexler H.

Grenzwerte am Arbeitsplatz und in der Umwelt: Philosophie und Umsetzung

ASU Arbeitsmed Sozialmed Umweltmed (2017) 

 

Klotz K., Weistenhöfer W., Neff F., Hartwig A., van Thriel C., Drexler H.

Gesundheitliche Auswirkungen einer Aluminiumexposition

Deutsches Ärzteblatt (2017) 

 

Strauch B.M., Niemand R.K., Winkelbeiner N.L., Hartwig A.

Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells

Particle and Fibre Toxicology (2017)

 

Piberger A. L., Krüger C., Strauch B. M., Schneider B., Hartwig A.

BPDE-induced genotoxicity: relationship between DNA adducts, mutagenicity in the in vitro PIG-A assay, and the transcriptional response to DNA damage in TK6 cells

Archives of Toxicology (2017)

 

Koch B., Maser E., Hartwig A.

Low concentrations of antimony impair DNA damage signaling and the repair of radiation-induced DSB in HeLa S3 cells

Archives of Toxicology (2017)

 

Lachenmeier D. W., Mildau G., Krause A., Marx G., Walch S. W., Hartwig A., Kuballa T.

Evaluation of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) in pure mineral hydrocarbon-based cosmetics and cosmetic raw materials using 1H NMR spectroscopy

F1000Research (2017)

 

Hartwig A., Jahnke G.

Metals and their compunds as contaminants in food: arsenic, cadmium, lead and aluminium

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (2017)

 

Olsen A. K., Dertinger S.D., Krueger C. T., Eide D. M., Instanes C., Brunborg G., Hartwig A., Graupner A.

The PIG-A gene mutation assay in mice and human cells: a review

Basic Clin Pharmacol Toxicol (2017)

 

Scheller J. S., Irvine G. W., Wong D. L., Hartwig A., Stillman M. J.

Stepwise copper(I) binding to metallothionein: a mixed cooperative and non-cooperative mechanism for all 20 copper ions

Metallomics (2017)

 

Bestgen S., Seidl C., Wiesner T., Zimmer A., Falk., Köberle B., Austeri M., Paradies J., Bräse S., Schepers U., Roesky P.W.

Double-Strand DNA breaks induced by paracyclophane gold(I) complexes

Chem Eur J  (2017) 

 

Fischer B.M., Hartwig A.

Aufklärung toxischer Wirkmechanismen mittels Hochdurchsatz-RT-qPCR

BIOsprektrum (2016)

 

Köberle B., Koch B., Fischer B.M., Hartwig A.

Single nucleotide polymorphisms in DNA repair genes and putative cancer risk

Arch Toxicol. (2016)

 

Cetraz M., Sen V., Schoch S., Streule, K., Golubev V., Hartwig A., Köberle B.

Platinum(IV)-nitroxyl complexes as possible candidates to circumvent cisplatin resistance in RT112 bladder cancer cells

Archives of Toxicology (2016)

 

Beyersmann D., Hartwig A.

Metalle Nickel

Handbuch Umweltmedizin (2016)

 

Krüger C.T., Fischer B.M. Armant O., Morath V., Strähle U., Hartwig A.

The in vitro PIG-A gene mutation assay: glycosylphosphatidylinositiol (GPI)-related genotype-to-phenotype relationship in TK6 cells

Archives of Toxicology (2016)

 

Fleck C. S., Sauter F., Pfeiffer E., Metzler M., Hartwig A., Köberle B.

DNA damage and repair kinetics of te Alternaria mycotoxins alternariol, altertoxin II and stemphyltoxin III in cultered cells

Mutation Research/Genetic Toxicology and Environmental Mutagenesis (2016)